What is the clinical evidence from this study?

Study design: Observational. Population: Depressive symptomatology (n=2723). Intervention: Low blood pressure vs. Normotension. Primary outcome: Center for Epidemiologic Studies Depression Scale (CES-D) score (p=<0.01).

March 1, 2000

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Relationship Between Low Blood Pressure and Depressive Symptomatology in Older People

Q: What are the key findings of this study?

Low blood pressure was significantly associated with increased depressive symptomatology in older Mexican Americans, with hypotensive subjects scoring a higher mean CES-D (12.07 vs 8.99; P<0.01).

CSChristine A. Stroup‐BenhamOffice of Education KMKyriakos S. MarkidesThe University of Texas Medical Branch at Galveston SBSandra A. BlackUniversity of Baltimore

Key Result

Low blood pressure was significantly associated with increased depressive symptomatology in older Mexican Americans, with hypotensive subjects scoring a higher mean CES-D (12.07 vs 8.99; P<0.01).

Study Design

Type

Observational (n=2,723)

Multicenter

Yes

Structured PICO

Is low blood pressure associated with depressive symptomatology and other somatic/psychological symptoms in older persons?

Population

2,723 Mexican Americans aged 65 or older not living in institutions in five southwestern states

Intervention

Low blood pressure (systolic hypotension)

Comparator

Normotension

Outcome

Depressive symptomatology measured by the Center for Epidemiologic Studies Depression Scale (CES-D)patient reported

Low blood pressure in older Mexican Americans is significantly associated with increased depressive symptoms, lower self-esteem, and poorer self-reported health.

Main Result

Absolute Event Rate: 12.07% vs 8.99%

p-value: p=<0.01

Abstract

OBJECTIVES : To determine if low blood pressure is associated with a definable constellation of somatic and psychological symptoms in older persons. DESIGN : A population‐based study. SETTING : In‐home interviews in five southwestern states. PARTICIPANTS : A total of 2723 Mexican Americans aged 65 or older not living in institutions. MEASURES : Blood pressure, Center for Epidemiologic Studies Depression Scale (CES‐D), global self‐rating of health, and self‐esteem. RESULTS : Bivariate analyses indicate a significant relationship between low blood pressure and increased depressive symptomatology; for example, systolic hypotensive subjects scored a CES‐D mean of 12.07 ± .67 compared to 8.99 ± .95 for normotensives ( P < .01). Regression analyses supported these findings when controlling for confounders such as gender, age, and use of antihypertensive medications. Subjects with low blood pressure also scored lower on self‐esteem and global self‐reported health and reported more days waking up feeling tired. CONCLUSIONS : These data support the existence of a relationship between low blood pressure and higher levels of depressive symptomatology as well as a constellation of somatic and psychosocial symptoms. J Am Geriatr Soc 48: 250–255, 2000 .

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Cite This Study

Stroup‐Benham et al. (Wed,) conducted a observational in Depressive symptomatology (n=2,723). Low blood pressure vs. Normotension was evaluated on Center for Epidemiologic Studies Depression Scale (CES-D) score (p=<0.01). Low blood pressure was significantly associated with increased depressive symptomatology in older Mexican Americans, with hypotensive subjects scoring a higher mean CES-D (12.07 vs 8.99; P<0.01).

synapsesocial.com/papers/6a0ec219a14f152feaf9cd17 https://doi.org/https://doi.org/10.1111/j.1532-5415.2000.tb02642.x

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