Heart failure in East Asia has a prevalence of 1.3% to 6.7% and total mortality of 2% to 9%, with adverse outcomes associated with age >65 years, diabetes, anaemia, renal dysfunction, and AF.
Heart failure remains a severe burden in East Asia with changing epidemiology and high mortality, highlighting the need for more region-specific prospective data.
Heart failure (HF) carries a major burden of disease in East Asia, with high associated risk of mortality and morbidity. In recent decades, the epidemiology of HF has changed with social and economical development in East Asia. The burden of HF is still severe in East Asia. The prevalence of HF ranges from 1.3% to 6.7% throughout the region. As aetiological factors, ischaemic heart disease has increased and valvular disease reduced in most East Asian countries. Diuretics are the most commonly used drugs (51.0%-97%), followed by renin-angiotensin system (RAS) inhibitors (59%-77%), with angiotensin-converting enzyme inhibitors, ACEI, (32%-52%) and has angiotensin-2 receptor blockers, ARBs (31%-44%) in similar proportions. Betablocker use has also increased in recent years. Total mortality from HF ranges from 2% to 9% in China, Taiwan, Singapore, Thailand, and Japan. Age>65 years, diabetes mellitus, anaemia, renal dysfunction and atrial fibrillation (AF) are associated with adverse outcome. More prospective, region-specific data are still required, particularly regarding new drug therapies such as eplerenone and ivabradine.
Guo et al. (Wed,) conducted a review in Heart failure. Heart failure in East Asia has a prevalence of 1.3% to 6.7% and total mortality of 2% to 9%, with adverse outcomes associated with age >65 years, diabetes, anaemia, renal dysfunction, and AF.
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