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Sharper image: A newly developed polysaccharide/drug conjugate (see picture) responds to changes in pH value and was shown to penetrate HeLa tumors in mice as determined by fluorescence imaging. It has the potential to be used in photodynamic therapy, thereby targeting the tumor while having no detrimental effects on the surrounding tissue. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Park et al. (Fri,) studied this question.