Worse eGFR category on admission for a first acute heart failure hospitalization was associated with a higher risk of one-year all-cause mortality (HR 1.378; p=0.030).
Cohort
Does admission renal impairment increase one-year mortality risk in patients with a first acute heart failure hospitalization?
Renal impairment at the time of first admission for acute heart failure is a significant predictor of one-year mortality.
Effect estimate: HR 1.378
p-value: p=0.030
INTRODUCTION AND OBJECTIVES: Chronic kidney disease is related to poor outcomes in patients with heart failure (HF). Few studies have assessed whether renal function influences one-year mortality risk in patients admitted for the first time for acute HF. METHODS: ). Index admission and one-year all-cause mortality rates were compared between groups using Cox regression analysis. RESULTS: . One-year all-cause mortality was 25.4%, with a significant association between worse eGFR category and mortality (p<0.0001). Cox regression analysis assessing eGFR as a categorical variable confirmed this association (HR 1.378; p=0.030), together with older age (HR 1.066; p<0.001), previous diagnosis of hypertension (HR 0.527; p<0.001), and both lower systolic blood pressure (HR 0.993; p=0.009) and higher serum potassium on admission (HR 1.471; p <0.001). CONCLUSIONS: Renal impairment is common in HF patients, even at the time of first admission. In this group of HF patients the presence of renal impairment was associated with higher mid-term (one-year) mortality risk.
Formiga et al. (Thu,) conducted a cohort in Acute heart failure. Renal impairment (worse eGFR category) was evaluated on One-year all-cause mortality (HR 1.378, p=0.030). Worse eGFR category on admission for a first acute heart failure hospitalization was associated with a higher risk of one-year all-cause mortality (HR 1.378; p=0.030).
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