March 10, 2011Open Access

Direct Alkylation of Heteroaryls Using Potassium Alkyl- and Alkoxymethyltrifluoroborates

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Abstract

A direct alkylation of various heteroaryls using stoichiometric potassium alkyl- and alkoxymethyltrifluoroborates has been developed. This method leads to the synthesis of complex substituted heterocycles, which have been obtained with yields up to 89%.

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Molander et al. (Thu,) studied this question.

synapsesocial.com/papers/6a100d91d13714ec96ff11d1 https://doi.org/https://doi.org/10.1021/ol2003572

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