A systematic review of 18 papers found no consistent pattern of either randomized controlled trials or non-randomized studies giving larger or smaller estimates of treatment effect.
Systematic Review
T he overall aim of the NHS R&D Health Technology Assessment (HTA) programme is to ensure that high-quality research information on the costs, effectiveness and broader impact of health technologies is produced in the most efficient way for those who use, manage
Britton et al. (Thu,) reported a systematic review. Randomised controlled trials vs. Non-randomised studies was evaluated on Treatment effect size. A systematic review of 18 papers found no consistent pattern of either randomized controlled trials or non-randomized studies giving larger or smaller estimates of treatment effect.