Area strain by 3D speckle tracking was independently associated with an increased risk of death or heart failure after acute myocardial infarction (HR 1.23; 95% CI 1.02-1.47; P=.03).
Cohort (n=96)
Does global left ventricular area strain by 3D speckle tracking predict death or hospitalization for heart failure in patients after acute myocardial infarction?
Global left ventricular area strain measured by 3D speckle tracking echocardiography provides incremental prognostic value for predicting death or heart failure hospitalization after acute myocardial infarction.
Effect estimate: HR 1.23 (95% CI 1.02-1.47)
p-value: p=.03
BACKGROUND: Three-dimensional (3D) speckle tracking echocardiography (STE) has been developed to overcome the limitations of two-dimensional (2D) STE and has been applied in the several clinical settings. However, no data exist about the prognostic value of 3DSTE-based strain on clinical outcome after myocardial infarction (MI). This study was designed to investigate the prognostic value of area strain (AS) by 3D speckle tracking in predicting clinical outcome after acute MI. METHODS: We assessed 96 patients (62±14 years, 72% male) with acute MI and who had undergone a coronary angiography. Clinical parameters and conventional echocardiographic measurements including the left atrial (LA) size and tissue Doppler measurements were evaluated. The global left ventricular (LV) AS was measured using 3D speckle tracking software. The relationship between the AS and clinical outcome of death or hospitalization for heart failure (HF) was assessed. RESULTS: During a median follow-up of 33±10 months, primary endpoint of death or HF occurred in 12 patients (12.5%). AS was predictive of death or HF after adjustment for age, gender, peak CK-MB, LA volume, LV end-systolic volume, LV mass, the ratio of early mitral inflow velocity to early mitral annular velocity, and LV ejection fraction in a multivariate Cox model (HR 1.23, 95% CI 1.02-1.47, P=.03). In addition, AS added incremental value in predicting death or heart failure on a model based on clinical and standard echocardiographic measures (P=.008). CONCLUSION: AS is independently associated with increased risk of death or HF after acute MI, suggesting that it can be a useful prognostic parameter in the patients following MI.
Shin et al. (Thu,) conducted a cohort in acute myocardial infarction (n=96). Area strain (AS) by 3D speckle tracking vs. Clinical and standard echocardiographic measures was evaluated on death or hospitalization for heart failure (HF) (HR 1.23, 95% CI 1.02-1.47, p=.03). Area strain by 3D speckle tracking was independently associated with an increased risk of death or heart failure after acute myocardial infarction (HR 1.23; 95% CI 1.02-1.47; P=.03).