The exactness of left ventricular segmentation in cine magnetic resonance imaging and its impact on systolic function values

Q: What is the clinical evidence from this study?

Study design: Cross-Sectional. Intervention: Manual tracing of myocardial borders vs. Computer-assisted quantification. Primary outcome: Exactness of segmentation estimated by the difference between end-systolic and end-diastolic left ventricular mass.

Key Result

Manual tracing of myocardial borders was more exact than computer-assisted quantification, where an ES-ED LVM difference >20 g led to a mean stroke volume measurement error of 8.8±3.6 ml.

Study Design

Type

Cross-Sectional (n=100)

PICO

Intervention / Comparator

Manual tracing of myocardial borders vs Computer-assisted quantification

Primary Outcome

Exactness of segmentation estimated by the difference between end-systolic and end-diastolic left ventricular mass

Abstract

PURPOSE: To evaluate the impact of exactness of the segmentation of the left ventricle (LV), using cine magnetic resonance imaging (MRI). MATERIAL AND METHODS: Steady-state free-precession cine MRI was performed on 100 randomly selected subjects. Myocardial borders were outlined on short-axis images using three methods: method 1 was computer assisted, excluding papillary muscles from the left ventricular mass (LVM); method 2 was similar but included papillary muscles; and method 3 was manually traced including papillary muscles. LV end-systolic (ES) and end-diastolic (ED) masses and volumes, ejection fraction (EF), stroke volume (SV), and cardiac output (CO) were calculated from these measurements. The difference between the ES and ED LVM was used to estimate the exactness of the methods. RESULTS: Method 3 was the most exact, and method 1 was the least exact. The three methods generated differing EF, SV, and CO measurements. With an ES-ED LVM difference exceeding 20 g, the mean SV measurement error was 8.8+/-3.6 ml. CONCLUSION: Manual tracing proved more exact than computer-assisted quantification. Exactness had an impact on EF, SV, and CO measurements, and the ES-ED LVM difference can be used to identify assessments that would benefit from more exact segmentation.

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Cite This Study

Barbier et al. (Sun,) reported a cross-sectional. Manual tracing of myocardial borders vs. Computer-assisted quantification was evaluated on Exactness of segmentation estimated by the difference between end-systolic and end-diastolic left ventricular mass. Manual tracing of myocardial borders was more exact than computer-assisted quantification, where an ES-ED LVM difference >20 g led to a mean stroke volume measurement error of 8.8±3.6 ml.

synapsesocial.com/papers/6a121c44f7bd4f5c7da5d137 https://doi.org/https://doi.org/10.1080/02841850601182154

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