Fluid-structure interaction analysis demonstrated that increased blood pressure reduces maximum wall shear stress, and the Carreau-Yasuda rheology model predicts up to 35% higher WSS than the Newtonian model.
Does high blood pressure alter Wall Shear Stress and Oscillatory Shear Index in normal and stenosed carotid artery models?
Computational fluid-structure interaction modeling demonstrates that high blood pressure reduces wall shear stress and alters oscillatory shear index in carotid arteries, contributing to our understanding of atherosclerosis hemodynamics.
Abstract Atherosclerosis is a localized complication dependent on both the rheology and the arterial response to blood pressure. Fluid–structure interaction (FSI) study can be effectively used to understand the local haemodynamics and study the development and progression of atherosclerosis. Although numerical investigations of atherosclerosis are well documented, research on the influence of blood pressure as a result of the response to physio–social factors like anxiety, mental stress, and exercise is scarce. In this work, a three-dimensional (3D) Fluid–Structure Interaction (FSI) study was carried out for normal and stenosed patient-specific carotid artery models. Haemodynamic parameters such as Wall Shear Stress (WSS) and Oscillatory Shear Index (OSI) are evaluated for normal and hypertension conditions. The Carreau–Yasuda blood viscosity model was used in the FSI simulations, and the results are compared with the Newtonian model. The results reveal that high blood pressure increases the peripheral resistance, thereby reducing the WSS. Higher OSI occurs in the region with high flow recirculation. Variation of WSS due to changes in blood pressure and blood viscosity is important in understanding the haemodynamics of carotid arteries. This study demonstrates the potential of FSI to understand the causes of atherosclerosis due to altered blood pressures.
Kumar et al. (Thu,) conducted a other in Atherosclerosis. High blood pressure and Carreau-Yasuda rheology model vs. Normal blood pressure and Newtonian rheology model was evaluated on Wall Shear Stress (WSS) and Oscillatory Shear Index (OSI). Fluid-structure interaction analysis demonstrated that increased blood pressure reduces maximum wall shear stress, and the Carreau-Yasuda rheology model predicts up to 35% higher WSS than the Newtonian model.