Earlier detection of peripartum cardiomyopathy with a diagnostic LVEF ≥0.35 is associated with better survival and higher full recovery rates compared to delayed diagnosis with LVEF <0.30.
Does earlier detection improve survival and recovery of heart function in women with peripartum cardiomyopathy?
Earlier detection of peripartum cardiomyopathy is crucial, as a higher LVEF at diagnosis (≥0.35) is associated with better survival and full recovery rates.
Peripartum cardiomyopathy (PPCM) has a remarkable potential for recovery. It may be within our capability to help almost all women with PPCM not only to survive, but also to completely recover heart function. Time-of-diagnosis left ventricular ejection fraction (LVEF) ≥0.35 is associated with better survival rates and higher full recovery rates. Increased mortality, chronic cardiomyopathy, thromboembolic complications and serious ventricular tachyarrhythmias are associated with diagnostic LVEF <0.30. Delays in diagnosis may result in lower LVEF at diagnosis and subsequent lower recovery rates. Greater awareness of the possibility of heart failure developing in previously healthy young women, with no history of heart disease, will contribute to earlier diagnosis, with potentially better preserved heart function. Women of African descent may be at higher risk for poorer outcomes. Recent investigations suggest newer biomarkers may help with earlier detection of PPCM.
James D. Fett (Fri,) conducted a review in Peripartum cardiomyopathy. Earlier detection was evaluated. Earlier detection of peripartum cardiomyopathy with a diagnostic LVEF ≥0.35 is associated with better survival and higher full recovery rates compared to delayed diagnosis with LVEF <0.30.