Baseline ECG criteria predicted inferolateral scar with 92% sensitivity and 90% specificity in preserved EF, and anteroseptal scar with 92% sensitivity and 81% specificity in dilated cardiomyopathy.
Observational (n=108)
Can baseline 12-lead ECG characteristics predict the location of scar (anteroseptal vs inferolateral) in patients with non-ischaemic cardiomyopathy and ventricular tachycardia?
Patients with non-ischaemic cardiomyopathy (NICM) and ventricular tachycardia can be categorized as anteroseptal (AS) or inferolateral (IL) scar sub-types based on imaging and voltage mapping studies. The aim of this study was to correlate the baseline electrocardiogram (ECG) with endo-epicardial voltage maps created during ablation procedures and identify the ECG characteristics that may help to distinguish the scar as AS or IL. We assessed 108 baseline ECGs; 72 patients fulfilled criteria for dilated cardiomyopathy whereas 36 showed minimal structural abnormalities. Based on the unipolar low-voltage distribution, the scar pattern was classified as predominantly AS (n = 59) or IL (n = 49). Three ECG criteria (PR interval 230 ms or QRS > 170 ms or an r ≤ 0.3 mV in V3 having 92 and 81% of sensitivity and specificity, respectively, in predicting AS scar pattern. A significant negative correlation was found between the extension of the endocardial unipolar low voltage area and left ventricular EF (rs = −0.719, P < 0.001). The extent of endocardial AS unipolar low voltage was correlated with PR interval and QRS duration (rs = 0.583 and rs = 0.680, P < 0.001, respectively) and the IL epicardial unipolar low voltage with the mean voltage of the limb leads (rs = −0.639, P < 0.001). Baseline ECG features are well correlated with the distribution of unipolar voltage abnormalities in NICM and may help to predict the location of scar in this population.
Olóriz et al. (Fri,) conducted a observational in Non-ischaemic cardiomyopathy and ventricular tachycardia (n=108). 12-lead electrocardiogram vs. Endo-epicardial voltage maps was evaluated on Correlation of baseline ECG with endo-epicardial voltage maps to distinguish anteroseptal or inferolateral scar. Baseline ECG criteria predicted inferolateral scar with 92% sensitivity and 90% specificity in preserved EF, and anteroseptal scar with 92% sensitivity and 81% specificity in dilated cardiomyopathy.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: