Questionnaire for quantitative assessment of treatment adherence: modification for adolescents aged 15–17 years, validation, and reliability assessment

In Russia, the QAA-25 questionnaire is used to quantify the adherence to treatment of adult patients. The accumulated experience of its use made it possible to identify several cohorts of respondents, including adolescents, whose characteristics required special adaptation of the formulations of a number of questions. Purpose . The study aimed at modifying the questionnaire for quantitative assessment of treatment adherence QAA-25 for adolescents aged 15–17 years and evaluate it according to the criteria of validity and the measure of consent. Material and methods . In a descriptive one-stage study with the participation of 108 high school students at secondary schools in Omsk, the level of adherence to treatment was determined according to the QAA-25 scale, using traditional and alternative formulations of individual questions, with the formation of a modified scale and an assessment of its constructive and factor validity and a measure of consent. Results . Applying various options for testing alternative questions, the possibility and expediency of using them to assess the adherence to treatment of adolescents, including separately evaluated subsamples of male and female individuals, was shown. 94% of respondents rated alternative questions as “more acceptable,» 5% of respondents «did not notice significant differences,» and 1% of respondents rated them as «less acceptable.» The QAA-25 scale modified for adolescents demonstrated good structural and internal validity (α = 0.818, α st = 0.857), with high reliability (consistent exclusion of scale items preserves the validity of the questionnaire in the range of 0.793–0.858) and almost perfect agreement (κ = 1.000). Conclusion . The modified QAA-25 questionnaire is recommended to be used to assess the adherence to treatment and potential adherence to treatment of adolescents who have reached the age of 15 but have not reached the age of 18, both for research purposes and when making decisions related to the provision of medical care and the organization of preventive measures.