Patients with obesity completing cardiac rehabilitation after acute coronary syndrome had higher relative improvement in exercise capacity than those without obesity (23.9% vs 17.6%, P=0.043).
Cohort (n=731)
Does a cardiac rehabilitation program improve exercise capacity and chronotropic index differently in patients with obesity compared to those without obesity after an acute coronary syndrome?
Patients with obesity derive significant, and potentially greater relative improvements in exercise capacity from cardiac rehabilitation after acute coronary syndrome compared to non-obese patients.
Absolute Event Rate: 23.9% vs 17.6%
p-value: p=0.043
PURPOSE: To evaluate the response of patients with obesity to a cardiac rehabilitation program (CRP), compared with patients without obesity. METHODS: We performed a retrospective analysis of 731 patients who completed phase II of a CRP after an acute coronary syndrome. The response to the CRP was assessed using the relative changes in exercise capacity (EC), resting heart rate (HR), and chronotropic index (CI). RESULTS: Only 23% of patients had obesity. Patients with obesity showed lower EC and CI at baseline and at the end of phase II of the CRP. Despite that, we reported a higher relative improvement for EC in patients with obesity (median interquartile range, 23.9% 5.2, 40.8 vs 17.6% 8.1, 35.9, P = .043) and similar improvements in CI (10.9% -1.4 to 34.2 vs 7.1% -7.1 to 28.2, P = .100), compared with patients without obesity. There were no significant changes in resting HR. CONCLUSION: Regardless of their lower exercise performance at baseline, patients with obesity had a remarkably positive response to the CRP compared with patients without obesity.
Braga et al. (Fri,) conducted a cohort in Acute coronary syndrome (n=731). Cardiac rehabilitation program (CRP) in patients with obesity vs. Patients without obesity was evaluated on Relative change in exercise capacity (EC) (p=0.043). Patients with obesity completing cardiac rehabilitation after acute coronary syndrome had higher relative improvement in exercise capacity than those without obesity (23.9% vs 17.6%, P=0.043).