Coronary artery bypass grafting improved mean physical and mental health at 1 year, but 29% of patients aged ≥80 years experienced decreased mental health compared to 20% in younger groups (P=0.039).
Cohort (n=2,606)
Yes
Does coronary artery bypass grafting improve quality of life across different age groups in patients undergoing elective surgery?
CABG generally improves physical and mental quality of life at 1 year, though a significant proportion of octogenarians experience a decline in mental health.
p-value: p=0.039
OBJECTIVES: In this study, our aim was to explore how coronary artery bypass grafting affects quality of life, and how this varies with age, particularly with patients at risk of deterioration. METHODS: In a retrospective, multicentre cohort study, patients with isolated coronary artery bypass grafting and electively operated between January 2011 and January 2015 with pre- and postoperative quality-of-life data were included. Patients were classified into 3 age groups: <65, 65-79 and ≥80 years. Quality of life was measured up to 1-year follow-up using the Short Form-12 or the Short Form-36 health survey. A multivariable, linear regression analysis, with an adjustment for confounders, was used to evaluate the association between age and quality of life. RESULTS: A total of 2606 patients were included in this study. Upon one-year of follow-up, the mean physical health of patients increased from 54 at baseline to 68, and mental health increased from 60 to 67. We observed decreased mental health in 20% of patients aged <65 years, 20% of patients aged 65-79 years and 29% of patients aged ≥80 years (P = 0.039). In this study, age was not associated with a lower physical or mental component score (P = 0.054 and P = 0.13, respectively). Independent risk factors for a decrease in quality of life consist of a better physical and mental score at baseline (P < 0.001) and a reduced left ventricular function (P < 0.001). CONCLUSIONS: Most patients experience a relevant increase in physical and mental quality of life, but a proportion of patients aged ≥80 years undergo significant deterioration in mental health.
Blokzijl et al. (Wed,) conducted a cohort in isolated coronary artery bypass grafting (n=2,606). Coronary artery bypass grafting vs. Age groups (<65, 65-79, ≥80 years) was evaluated on Quality of life (Short Form-12 or Short Form-36) (p=0.039). Coronary artery bypass grafting improved mean physical and mental health at 1 year, but 29% of patients aged ≥80 years experienced decreased mental health compared to 20% in younger groups (P=0.039).