Patients with diabetes and hypertension had significantly increased right common carotid artery intima media thickness compared to normal subjects (0.659 mm vs 0.589 mm, p=0.022).
Cross-Sectional (n=200)
No
Do diabetes and hypertension alter carotid artery hemodynamics compared to normal subjects?
Patients with diabetes and hypertension have significantly altered carotid artery hemodynamics, including increased intima-media thickness and end-diastolic velocity.
Absolute Event Rate: 0.659% vs 0.589%
p-value: p=0.022
Diabetic and hypertensive patients are at increased risk of vascular complications. Carotid Doppler ultrasonography serves as a non-invasive gold standard technique/tool to access and monitor carotids hemodynamics and morphology. There is a need to predict difference in carotid artery hemodynamics among hypertensive and diabetic patients.Aim: Aim of this study is to find out the hemodynamics of carotid artery in diabetic and hypertensive patients. Method: Cross sectional study conducted at University Ultrasound Clinic Green Town. All patients were investigated with Toshiba Xario XG with 5-7.5MHz linear probe. Study included diabetic and hypertensive individuals, whereas patients with history of carotid endarterectomy, carotid stenting and co-morbidity were excluded. Total 200 participants were recruited, 41 were diabetic and hypertensive, while 159 were normal subjects. Statistical analysis was performed using SPSS version 21. Results: From 200 participants were recruited, out of them 41 patients with 20.5% were positive with diabetes and hypertension and 159 patients with 79.5% were negative with diabetes and hypertension. Right common carotid artery intima media thickness (IMT) mean ± S.D was 0.659±0.114mm with p-value (0.022). Left common carotid end diastolic velocity mean ± S.D was 16.719±6.303cm/s with p-value (0.002). Conclusion: The study highlighted that common carotid artery intima media thickness (IMT) and common carotid artery end diastolic velocity were significantly correlated with hypertension and diabetes. Our findings revealed that common carotid artery IMT and EDV were significant in hypertensive and diabetic patients. Indeed, hypertension and diabetes are mainly associated with vascular complications.
Fatima et al. (Sun,) conducted a cross-sectional in Diabetes and Hypertension (n=200). Diabetes and Hypertension (Exposure) vs. Normal subjects was evaluated on Right common carotid artery intima media thickness (IMT) in mm (p=0.022). Patients with diabetes and hypertension had significantly increased right common carotid artery intima media thickness compared to normal subjects (0.659 mm vs 0.589 mm, p=0.022).