PURPOSE: = 46 eyes). METHODS: < 0.05). RESULTS: Vision at presentation, 1 week-2 months, and 2-3 months did not differ significantly between MRSA and MSSA in exogenous or endogenous groups. The exogenous cohort had significantly higher rates of enucleation/evisceration than the endogenous cohort. Intravenous drug use and mortality were more frequent among patients with endogenous MRSA, though not statistically significant. CONCLUSION: MRSA and MSSA endophthalmitis have similar ocular outcomes. In exogenous and endogenous cohorts, there were no significant differences in vision or complications between MRSA and MSSA endophthalmitis except that the exogenous group had a significantly higher rate of enucleation/evisceration, potentially reflecting increased organism load with direct inoculation. The higher mortality associated with endogenous MRSA infections, though not statistically significant, warrants future investigation.
Katragadda et al. (Tue,) studied this question.