BACKGROUND: In the present study, we aimed to comprehensively describe the full clinical course of dead bag syndrome (DBS) presenting 17 months after cataract surgery, and to elucidate its clinical characteristics, histopathological features. CASE PRESENTATION: A 55-year-old man presented with progressive blurred vision in his left eye 17 months following an uncomplicated cataract extraction. Ophthalmic examination revealed a lax, translucent capsular bag accompanied by partial dislocation of the intraocular lens (IOL)-capsular bag complex. Histopathological analysis showed extensive depletion of lens epithelial cells (LECs), multilayer delamination of the capsular bag, and markedly reduced fibronectin expression. The patient subsequently underwent removal of the displaced IOL and scleral-sutured implantation of a new IOL, which led to substantial postoperative visual recovery. CONCLUSION: This case indicated that DBS could manifest within a relatively short postoperative interval. Histopathological analysis showed structural alterations of the capsular bag consistent with DBS following cataract surgery. Accordingly, DBS should be recognized as a potential complication and carefully considered during routine postoperative surveillance following cataract surgery.
Jiang et al. (Tue,) studied this question.