Alcohol-related hospitalizations among cancer patients increased significantly from 2016 to 2021 (P<0.001), with male sex strongly associated with admission (OR 3.18; 95% CI 2.90-3.47).
Observational (n=12,027,846)
Yes
Alcohol-related hospitalizations among cancer patients are rare (0.13%) but significantly increasing, with risk factors mirroring those in the general population.
Effect estimate: 0.008% increase per year
p-value: p=<0.001
10624 Background: Alcohol consumption is associated with an increased risk of developing multiple cancers and has been linked to higher cancer-related mortality. Alcohol dependence and harmful alcohol use may also compromise oncologic care and worsen the clinical course. However, little is known about the prevalence and outcomes of alcohol-related hospitalizations among patients with cancer. Methods: We analyzed trends and risk factors of alcohol-related hospitalizations among adults with cancer using the National Inpatient Sample database for the years 2016-2021. Alcohol-related admissions were identified using ICD-10 codes for intoxication, withdrawal, alcohol-induced mood and psychotic disorders, and other alcohol-induced disorders. Prevalence estimates were adjusted using discharge-level weights to represent national data. Linear and multivariate logistic regression were used to assess trends in alcohol-related admissions and associations with sociodemographic and clinical characteristics. Results: Among 12,027,846 non-elective hospitalizations for patients with cancer, 15,205 (0.13%) were alcohol related. From 2016 to 2021, we observed an average increase of 185 admissions per year (from 2130 to 3200, P = 0.009). After adjusting for all non-elective hospitalizations in cancer patients, the linear time trend in alcohol-related admissions increased by an average of 0.008% per year ( P 70 1.72 (1.18-2.53)5.96 (5.11-6.94)4.25 (3.78-4.79)1 (reference) Race/ethnicityWhiteBlackHispanicAsianOther 1 (reference)0.57 (0.51-0.66)0.51 (0.43-0.60)0.15 (0.10-0.26)0.67 (0.56-0.81) Hospital locationUrbanRural 1 (reference)1.29 (1.11-1.50) Housing instability 5.84 (5.00-6.84) Opioid use disorder 2.37 (2.01-2.81) Depressive disorder 3.51 (3.23-3.82) Psychotic disorder 1.27 (1.01-1.61)
Mehlich et al. (Wed,) conducted a observational in Cancer (n=12,027,846). Alcohol-related hospitalizations was evaluated on Trends in alcohol-related admissions (0.008% increase per year, p=<0.001). Alcohol-related hospitalizations among cancer patients increased significantly from 2016 to 2021 (P<0.001), with male sex strongly associated with admission (OR 3.18; 95% CI 2.90-3.47).
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