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Book reviews SPECT brain images using IMP and other compounds relate to cerebral blood flow and that thus the most promising applica- tions of this technique concerns cere- brovascular diseases.However, two papers deal with brain tumours, one with epilepsy, and three present only a few case reports of patients with vascular problems.The last paper only (using HIPDM) mentions a larger number of cerebrovascular patients but is rather superficial.In general the clin- ical significance of the scan results is not clear: abnormal patterns of radionuclide distribution may be proportionate within (unknown) limits to tissue perfusion dis- turbances, but only speculations are given how that information can be used in a clin- ical setting.A big handicap is that no abso- lute quantitation can be achieved with SPECT.It has to be admitted, however, that the data presented in the book are pre- liminary.On the other hand Schober and colleagues present a nice study comparing
P. Macpherson (Tue,) studied this question.