Background: The rise in AMR has intensified the search for alternative therapies, including those derived from the traditional systems of medicine. Several plant-based compositions known for their antibacterial qualities are used in Siddha, one of the oldest traditional medical systems still in use in South India. Aim and Objectives: This study aims to assess the antibacterial potential of four Siddha preparations (Nilavembu Kudineer, Thippili Rasayanam, Kandankathiri Kudineer, and Karpoora Chooranam) against clinically important bacterial strains. Materials and Methods: Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Klebsiella pneumoniae are clinically significant bacterial strains that are tested for antibacterial efficacy in this study using four widely used Siddha preparations: Thippili Rasayanam, Nilavembu Kudineer, Kandankathiri Kudineer, and Karpoora Chooranam. Each of the four formulations was tested for antibacterial activity using the agar well-diffusion method. Results: The findings show that several Siddha formulations have strong antibacterial properties, with Nilavembu Kudineer showing the largest zone of inhibition against E. coli and S. aureus . Conclusion: These findings underscore the potential of Siddha medicines as alternative or complementary antimicrobial agents.
Akilan et al. (Tue,) studied this question.