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Integrins are a major family of cell-surface-adhesion receptors that are expressed in all metazoans. They are heterodimers of noncovalently associated α and β subunits, each of which is a single-pass type I transmembrane protein (Humphries et al., 20061; Hynes, 20022). The specific binding
Harburger et al. (Wed,) studied this question.