Key points are not available for this paper at this time.
• Comprehensive review of the sources and mechanisms underlying tumor heterogeneity. • Multiple approaches, including multi-regional and liquid biopsies, enable effective monitoring of tumor heterogeneity, which can inform and improve therapeutic strategies. • Precision medicine offers strategies to manage and therapeutically exploit tumor heterogeneity and guide future cancer therapies.
Lv et al. (Fri,) studied this question.