His bundle pacing in a patient with CHF and LBBB resulted in dramatic clinical improvement over 27 months, with NYHA class improving from IV to I and ejection fraction increasing from 28% to 50%.
Case Report (n=1)
Does His bundle pacing improve clinical and echocardiographic outcomes in a patient with congestive heart failure and left bundle branch block?
His bundle pacing may serve as an effective alternative to standard biventricular pacing for achieving physiologic resynchronization and reversing heart failure in patients with LBBB.
Physiologic Resynchronization Therapy. This is a case of a patient with congestive heart failure and left bundle branch block who was referred for cardiac resynchronization therapy implantation. Instead, a His bundle pacing was achieved with a narrow QRS complex. During 27 months of observation, the patient improved dramatically from NYHA class IV to I. Echo parameters improved significantly the LV diameter from 75/50 to 60/40 mm, EF from 28 to 50%, and mitral regurgitation from 4 to 2°. (J Cardiovasc Electrophysiol, Vol. 22, pp. 813-817, July 2011)
Dąbrowski et al. (Thu,) conducted a case report in Congestive heart failure and left bundle branch block (n=1). His bundle pacing was evaluated on NYHA class and echocardiographic parameters (LV diameter, ejection fraction, mitral regurgitation). His bundle pacing in a patient with CHF and LBBB resulted in dramatic clinical improvement over 27 months, with NYHA class improving from IV to I and ejection fraction increasing from 28% to 50%.