Cardiomyocyte-specific BDNF knockout in mice was profiled using single-nucleus RNA sequencing to reveal its effects on cardiac cell phenotypes and pathophysiological mechanisms.
Single-nucleus RNA sequencing characterizes the cellular and phenotypic changes in the heart following cardiomyocyte-specific BDNF knockout.
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Single-nucleus RNA sequencing was applied to reveal the effects of cardiomyocytes specific knockout BDNF gene in the clusters and phenotype of cardiac constituent cells, as well as the mechanisms underlying cardiac physiology and pathology in the cardiomyocyte-specific BDNF conditional knockout heart.
朱宇(yu zhu) (Sun,) reported a other. Cardiomyocyte-specific BDNF knockout in mice was profiled using single-nucleus RNA sequencing to reveal its effects on cardiac cell phenotypes and pathophysiological mechanisms.