Does the triglyceride to HDL cholesterol ratio (THR) correlate with and predict poor blood pressure control in patients with primary hypertension?
A higher triglyceride to HDL cholesterol ratio is associated with poorly controlled blood pressure in hypertensive patients and may serve as a predictor to identify those needing closer monitoring.
Abstract Hypertension (HT) is associated with significant morbidity and mortality. The efficacy of the treatment in HT patients is mostly depending on the office or home blood pressure monitoring. Triglyceride to high density lipoprotein (HDL) cholesterol ratio (THR) is an inflammatory and metabolic predictor. We aimed to compare THR levels of the HT patients with poorly controlled blood pressure levels to those with well‐controlled hypertensive subjects. In present cross sectional study, we grouped patients with HT either as well or poorly controlled hypertensive subjects according to the blood pressure measurement. THR of the groups compared. The THR of the poorly controlled HT group (3.9 1.91–88.7%) was significantly higher than the THR of the well‐controlled HT group (3.07 0.71–35.8%), ( p < .001). The sensitivity and specificity of THR higher than 3.26% in predicting poor blood pressure control were 72% and 52%, respectively (AUC: 0.64, p <.01, %95 CI: %59–70). High THR levels in HT patients may warrant closer monitorization of blood pressure since it may predict poor blood pressure control in this population.
Kurtkulağı et al. (Tue,) studied this question.
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