Effect of rapamycin on human periodontal ligament stem cells

Key Points

• This research aims to explore the effects of rapamycin on human periodontal ligament stem cells.
• Human periodontal ligament stem cells were cultured and treated with rapamycin.
• Various assays measured cell proliferation and differentiation outcomes.
• Rapamycin significantly inhibited cell proliferation compared to untreated controls.
• Evidence of altered differentiation pathways was observed in stem cells exposed to rapamycin.