Photoaging of Primary Melanocytes Induced by UV Radiation is Attenuated by SEH Inhibition

Key Points

• This research examines the effects of SEH inhibition on UV radiation-induced photoaging in primary melanocytes.
• Experimental groups included UV group (75 mJ cm² UVA + 75 mJ cm² UVB), SEH pretreatment group, and WT group.
• Various treatments were applied to assess photoaging effects on melanocytes.
• The SEH pretreatment group exhibited reduced signs of photoaging compared to the UV group.
• Results indicate that SEH inhibition may play a protective role against UV-induced damage.