The Glabella wearable device's computed pulse transit times showed a high correlation with systolic blood pressure measured by oscillometric cuffs (mean r = 0.79).
Observational (n=4)
Does the Glabella wearable device accurately estimate systolic blood pressure compared to a commercial oscillometric cuff in human participants?
A novel glasses-integrated wearable device demonstrated high correlation with standard cuff-based systolic blood pressure measurements, suggesting potential for continuous, unobtrusive monitoring.
Effect estimate: mean r = 0.79
We propose Glabella, a wearable device that continuously and unobtrusively monitors heart rates at three sites on the wearer’s head. Our glasses prototype incorporates optical sensors, processing, storage, and communication components, all integrated into the frame to passively collect physiological data about the user without the need for any interaction. Glabella continuously records the stream of reflected light intensities from blood flow as well as inertial measurements of the user’s head. From the temporal differences in pulse events across the sensors, our prototype derives the wearer’s pulse transit time on a beat-to-beat basis. Numerous efforts have found a significant correlation between a person’s pulse transit time and their systolic blood pressure. In this paper, we leverage this insight to continuously observe pulse transit time as a proxy for the behavior of systolic blood pressure levels—at a substantially higher level of convenience and higher rate than traditional blood pressure monitors, such as cuff-based oscillometric devices. This enables our prototype to model the beat-to-beat fluctuations in the user’s blood pressure over the course of the day and record its short-term responses to events, such as postural changes, exercise, eating and drinking, resting, medication intake, location changes, or time of day. During our in-the-wild evaluation, four participants wore a custom-fit Glabella prototype device over the course of five days throughout their daytime job and regular activities. Participants additionally measured their radial blood pressure three times an hour using a commercial oscillometric cuff. Our analysis shows a high correlation between the pulse transit times computed on our devices with participants’ heart rates (mean r = 0.92, SE = 0.03, angular artery) and systolic blood pressure values measured using the oscillometric cuffs (mean r = 0.79, SE = 0.15, angular-superficial temporal artery, considering participants’ self-administered cuff-based measurements as ground truth). Our results indicate that Glabella has the potential to serve as a socially-acceptable capture device, requiring no user input or behavior changes during regular activities, and whose continuous measurements may prove informative to physicians as well as users’ self-tracking activities.
Holz et al. (Mon,) reported a observational. Glabella wearable device vs. Commercial oscillometric cuff was evaluated on Correlation between pulse transit times and systolic blood pressure values (mean r = 0.79). The Glabella wearable device's computed pulse transit times showed a high correlation with systolic blood pressure measured by oscillometric cuffs (mean r = 0.79).
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