This study aimed to intensify the ultrasound-assisted extraction (UAE) of rutin, chlorogenic acid, ferulic acid, and total phenolic compounds (TPCs) from mangaba (Hancornia speciosa Gomes) fruit. Based on a univariate experimental screening, the selected operational conditions for the recovery of TPC, chlorogenic, and ferulic acids were achieved at an ultrasonic frequency of 40 kHz with an output power of 145 W (100% potency), atmospheric pressure, and 35 °C for 30 min. Under these conditions, the extraction yields were 1750.16 ± 0.66 mg GAE/100 g for TPC, 183.86 ± 4.53 mg/100 g for chlorogenic acid, and 2.19 ± 0.3 mg/100 g for ferulic acid. Conversely, the highest rutin concentration (157.17 ± 4.68 mg/100 g) was obtained at 145 W, atmospheric pressure, and 30 °C for 30 min. Increasing the ultrasonic potency from 30% to 100% significantly enhanced the extraction of chlorogenic acid, ferulic acid, and TPC, whereas it had no significant impact on rutin recovery. These results demonstrate that time, temperature, and ultrasonic potency are critical drivers of process efficiency. This work establishes a technical baseline for the industrial scale-up of UAE, highlighting its potential for the high-yield production of bioactive extracts from native Brazilian fruits for the pharmaceutical and food sectors.
Santos et al. (Mon,) studied this question.