Diabetes mellitus was associated with significantly increased left ventricular posterior wall thickness (11.4 vs 9.4 mm, p<0.01) and left ventricular mass compared to healthy controls.
Cross-Sectional (n=42)
No
Does diabetes mellitus alter echocardiographic parameters of left ventricular wall thickness and mass in patients without clinical coronary artery disease?
Diabetic patients without clinical coronary artery disease exhibit increased left ventricular wall thickness and mass, suggesting early structural changes consistent with diabetic cardiomyopathy.
Mean Difference: 2
Absolute Event Rate: 11.4% vs 9.4%
p-value: p=<0.01
The results of echocardiographic examination of 23 diabetics are presented. Significantly increased left ventricular posterior wall thickness and mass and elevated ratio of wall thickness to chamber radius were found in the group of diabetic patients without coronary artery disease and hypertension. The interventricular septum thickness was significantly increased only in the diabetics with hypertension. The possible causes of these findings may be the presence of microangiopathy at the periphery of the coronary circulation or the presence of PAS-positive substances with resulting interstitial fibrosis.
Gregor et al. (Sun,) conducted a cross-sectional in Diabetes mellitus (n=42). Diabetes mellitus vs. Healthy controls was evaluated on Left ventricular posterior wall thickness (mm) (MD 2.0, p=<0.01). Diabetes mellitus was associated with significantly increased left ventricular posterior wall thickness (11.4 vs 9.4 mm, p<0.01) and left ventricular mass compared to healthy controls.
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