Admission blood pressure in acute stroke declined with increasing time from onset (8/4 mm Hg) and was independently increased by prior hypertension (systolic +16.3 mm Hg, diastolic +8.6 mm Hg).
Observational
In acute stroke, admission blood pressure is independently associated with factors like prior hypertension, hemorrhage, age, and ischemic heart disease, but not with initial stroke severity.
This study examines blood pressure (BP) and independent factors related to BP in the acute phase of stroke. The study is part of the community-based Copenhagen Stroke Study. In a multivariate regression model we analyzed the impact of clinical and medical factors on admission BP. BP declined with increasing time from stroke onset with a total of 8/4 mm Hg. Independent factors related to diastolic BP were ischemic heart disease (-3.9 mm Hg), male gender (2.2 mm Hg), known hypertension prior to stroke (8.6 mm Hg), and primary hemorrhage (9.7 mm Hg). Independent factors related to systolic BP were age (3.6 mm Hg/10-year increase), atrial fibrillation (-7.2 mm Hg), ischemic heart disease (-6.0 mm Hg), intracerebral hemorrhage (13.3 mm Hg), and known hypertension prior to stroke (16.3 mm Hg). No independent relations were seen between BP and diabetes, claudication, previous stroke, smoking, daily alcohol consumption, initial stroke severity and lesion size. The increase in BP in the acute phase of stroke is a uniform response to the ischemic event per se. BP is not related to stroke severity. Several factors are independently related to the BP level in acute stroke. The clinical significance of this is yet to be tested, but these factors may contribute to the seemingly complex relation between BP and outcome.
Jørgensen et al. (Tue,) conducted a observational in Acute stroke. Clinical and medical factors was evaluated on Admission blood pressure. Admission blood pressure in acute stroke declined with increasing time from onset (8/4 mm Hg) and was independently increased by prior hypertension (systolic +16.3 mm Hg, diastolic +8.6 mm Hg).
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