A 62-year-old male developed a left atrial myxoma approximately four years after undergoing a transseptal radiofrequency ablation for atrial fibrillation, suggesting a potential iatrogenic causation.
Case Report (n=1)
This case report suggests a potential, though unproven, iatrogenic link between transseptal puncture during cardiac ablation and the subsequent development of a left atrial myxoma.
Background: Cardiac myxomas are benign cardiac neoplasms usually found solitarily located within a single cardiac chamber, most commonly in the left atrium. With no established cause, they are often thought to occur spontaneously with no particular genetic cause or external incitement. While it has been explored, there is no universally accepted correlation with myxoma formation following a cardiac ablation procedure. We propose the theory of an iatrogenic causation of cardiac myxoma formation, likely incited by the local tissue injury during the transseptal puncture of the interatrial wall. Case Summary: We present the case of a 62-year-old male with a medical history significant for Atrial Fibrillation for which he underwent a transseptal ablation procedure, during which a puncture is made through the interatrial septum. Transthoracic and transesophageal echocardiograms obtained prior to the procedure did not reveal any intracardiac masses or abnormalities. 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Ganthan et al. (Wed,) conducted a case report in Cardiac myxoma (n=1). Transseptal radiofrequency ablation was evaluated on Development of cardiac myxoma. A 62-year-old male developed a left atrial myxoma approximately four years after undergoing a transseptal radiofrequency ablation for atrial fibrillation, suggesting a potential iatrogenic causation.