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Evaluating the impact of applications with significant operating-system interactions requires detailed microarchitectural simulation combined with system-level simulation. A cost-effective and practical approach is to combine two widely used simulators. SimWattch integrates Simics, a system-level tool, with Wattch, a user-level tool, to facilitate analysis of a wider design space for computer architects and system developers.
Chen et al. (Sun,) studied this question.
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