In patients with subarachnoid hemorrhage, a prolonged QTc interval independently predicted myocardial injury (OR 8, p=0.01), and T wave inversion predicted ventricular dysfunction (OR 4.4, p=0.02).
Observational (n=227)
Continuous 12-lead ECG monitoring reveals a high prevalence of ECG abnormalities in SAH patients, with specific changes like prolonged QTc and T wave inversion independently predicting myocardial injury and ventricular dysfunction.
Odds Ratio: 8
p-value: p=0.01
Subarachnoid hemorrhage is a serious neurological disorder that is often complicated by the occurrence of electrocardiographic abnormalities unexplained by preexisting cardiac conditions. These morphological waveform changes and arrhythmias often are unrecognized or misinterpreted, potentially placing patients at risk for inappropriate management. Many previous investigations were retrospective and relied on data collected in an unsystematic manner. More recent studies that included use of serial electrocardiograms and Holter recordings have provided new insight into the high prevalence of electrocardiographic changes in subarachnoid hemorrhage. Research on the prevalence, duration, and clinical significance of these electrocardiographic abnormalities and on associated factors and etiological theories is reviewed.
Claire E. Sommargren (Tue,) conducted a observational in Subarachnoid hemorrhage (n=227). Prolonged QTc interval vs. Normal QTc interval was evaluated on Myocardial injury (OR 8, p=0.01). In patients with subarachnoid hemorrhage, a prolonged QTc interval independently predicted myocardial injury (OR 8, p=0.01), and T wave inversion predicted ventricular dysfunction (OR 4.4, p=0.02).