Vasospastic angina patients with acute myocardial infarction exhibited significantly higher rates of multivessel (76% vs 57%) and diffuse (86% vs 59%) coronary spasm compared to those without infarction.
Observational (n=292)
No
What are the clinical and angiographic characteristics of acute myocardial infarction caused by vasospastic angina?
Acute myocardial infarction caused by vasospastic angina is often the first symptom of the condition, is frequently preceded by emotional stress, and is associated with more multivessel and diffuse coronary spasm.
Absolute Event Rate: 76% vs 57%
p-value: p=0.008
BACKGROUND: Vasospastic angina (VA) can occasionally cause acute myocardial infarction (AMI). METHODS AND RESULTS: From January 2003 to June 2005, coronary spastic angina was diagnosed in 292 patients by performing spasm provocation tests. Among the 292 patients, 21 (7.2% of all the VA patients) had an AMI. There were 20 patients who initially visited the emergency room for AMI without suffering prior VA. One patient with a history of VA had an AMI when he discontinued his medication. Among the 21 VA patients with AMI, 14 had experienced severe emotional stress before they visited the emergency room. The spasm provocation test showed that the VA patients with AMI had more multivessel and diffuse spasm than the VA patients without AMI (p<0.001). CONCLUSION: Clinically, the VA patients with AMI usually had their first symptom of VA as the severe chest pain of AMI. Two-thirds of the VA patients with AMI had experienced emotional stress before their AMI. Angiographically, the spasm provocation test for VA patients with AMI showed more multivessel and diffuse spasm than in VA patients without AMI.
Kim et al. (Mon,) conducted a observational in Vasospastic angina (n=292). Acute myocardial infarction vs. No acute myocardial infarction was evaluated on Multivessel coronary spasm during provocation test (p=0.008). Vasospastic angina patients with acute myocardial infarction exhibited significantly higher rates of multivessel (76% vs 57%) and diffuse (86% vs 59%) coronary spasm compared to those without infarction.