Objective: To evaluate pathological findings in patients positive for human papillomavirus (HPV)-31. Material and Methods: This retrospective study included patients evaluated in a tertiary colposcopy clinic.The 3,546 patients tested for high-risk HPV were evaluated from September 2019 to December 2023.The study comprised 130 (3.7%) patients who tested positive for HPV-31.Isolated HPV-31 positivity indicated the presence of HPV-31 alone.Combined positivity indicated coexistence with other high-risk HPV types.If the following lesions were positive, high-grade squamous intraepithelial lesions (HSILs), adenocarcinoma in situ, microinvasive cancer, and cervical cancer, we classified the final pathology as ≥HSIL.Statistical analysis was performed using IBM SPSS Statistics version 20.0. Results:The mean age was 44.4±9.24years.Isolated HPV-31 positivity was present in 69 (53.1%) patients.The final pathologic result was ≥HSIL in 9 (6.9%) patients, with only 1 (0.8%) patient had squamous cell cervical cancer.No significant association was observed between HPV-31 positivity type (isolated or combined) and ≥HSIL (respectively, 7.2% vs. 6.6%;p=0.578). Conclusion:Approximately 7% of women positive for HPV-31 have HSIL and higher lesions.The isolated or combined HPV-31 positivity does not affect the existence of HSIL or higher lesions.[
Buran et al. (Tue,) studied this question.