This review summarizes knowledge concerning warfarin use in routine practice, focusing on bleeding risks, thrombotic complications, and drug-drug interactions.
This review highlights the practical challenges of warfarin therapy, including bleeding, thrombosis, and drug interactions, which are highly relevant for cardiologists and emergency physicians.
The increased frequency of referral of patients with warfarin related complications to the emergency unit is worthy of our attention nowadays. The most common reason for this is its role in the prevention of stroke in atrial fibrillation and increased usage of this drug for the high rate of valve surgery. Bleeding in case of a supratherapeutic effect, its relation with thrombotic complications at subtherapeutic levels and additionally the presence of high risk of drug-drug interaction are important aspects of this drug in routine practice of the cardiologist and emergency physician. Our aim is to review knowledge concerning warfarin in routine practice. (JAEM 2013; 12: 38-42)
Altunbaş et al. (Tue,) conducted a review in Warfarin related complications. Warfarin was evaluated. This review summarizes knowledge concerning warfarin use in routine practice, focusing on bleeding risks, thrombotic complications, and drug-drug interactions.