Richard J. Cook, Vern T. Farewell, Multiplicity Considerations in the Design and Analysis of Clinical Trials, Journal of the Royal Statistical Society. Series A (Statistics in Society), Vol. 159, No. 1 (1996), pp. 93-110

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Cook et al. (Mon,) studied this question.

synapsesocial.com/papers/6a225f899ffd75766f4634ed https://doi.org/https://doi.org/10.2307/2983471

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Design of Experiments1936 · 4,224 citations
2Repeated Significance Tests on Accumulating Data1969 · 778 citations
3Evaluation of bed rest in threatened abortion.1953 · 16 citations
4A Generalization of a Nonparametric Test for Stochastically Ordered Distributions to Censored Survival Data1988 · 15 citations
5Statistical Methods for Research Workers1945 · 11,049 citations