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The eggs of Caenorhabditis elegans and Drosophila bear little similarity to each other, yet both depend on the par genes for control of anterior-posterior polarity. Here we explore possible common roles for the par genes ( par s) in converting transient asymmetries into stably polarized axes. Although clear mechanistic parallels remain to be established, par -dependent regulation of microtubule dynamics and protein stability emerge as common themes.
Pellettieri et al. (Thu,) studied this question.