Undergoing delayed PCI on the second week (day 14) after STEMI was associated with the lowest incidence of major adverse cardiovascular events in stable patients without early reperfusion.
Cohort
Does performing delayed PCI during the second week reduce major adverse cardiovascular events compared to earlier intervention in stable STEMI patients who missed early reperfusion?
For stable STEMI patients who miss early reperfusion, delayed PCI performed during the second week (around day 14) is associated with the lowest incidence of major adverse cardiovascular events.
p-value: p=0.007
OBJECTIVE: There are still a high proportion of patients with ST-segment elevation myocardial infarction (STEMI) missing out early reperfusion even in the primary percutaneous coronary intervention (PCI) era. Most of them are stable latecomers, but the optimal time to undergo delayed PCI for stable ones remains controversial. METHODS: We investigated all STEMI patients who underwent delayed PCI (2-28 days after STEMI) during 2007-2010 in Beijing and excluded patients with hemodynamic instability. The primary outcome was major adverse cardiovascular events (MACEs). RESULTS: = 0.007) than Early group in pairwise comparisons. We depicted the incidence of major adverse cardiovascular event (MACE) by delayed time as a quadratic curve and found the bottom appeared at day 14. CONCLUSIONS: The delayed PCI time varied in the real-world practice, but undergoing operations on the second week after STEMI had greater survival benefit and less adverse events for whom without early reperfusion and hemodynamic instability.
Zheng et al. (Tue,) conducted a cohort in ST-segment elevation myocardial infarction (STEMI). Delayed PCI on the second week (day 14) vs. Early group / other delayed times was evaluated on major adverse cardiovascular events (MACEs) (p=0.007). Undergoing delayed PCI on the second week (day 14) after STEMI was associated with the lowest incidence of major adverse cardiovascular events in stable patients without early reperfusion.