Six to 8 years after acute deep-vein thrombosis, 42% of patients had died, primarily from preexisting cancer or cardiovascular disease, while recurrent venous thromboembolism occurred in 15%.
Cohort (n=124)
Long-term follow-up of DVT patients reveals high mortality driven by preexisting cancer or cardiovascular disease, relatively low VTE recurrence, but frequent postphlebitic symptoms that negatively impact quality of life.
Objective: To assess the long-term outcomes of patients with acute deep-vein thrombosis. Methods: We followed up 124 patients with deep-vein thrombosis 6 to 8 years after the index thrombosis to determine the frequency of death, recurrent venous thromboembolism, postphlebitic symptoms, and their relationship to three domains of health-related quality of life. Results: Fifty-two (42%) of the 124 patients died. The cumulative incidence of death was 17% at 1 year and 39% at 5 years. Death was especially common among patients older than 75 years and those with cancer or stroke (5-year cumulative incidence, 66%, compared with 12% among other patients;PPPConclusions: Six to 8 years after deep-vein thrombosis, many patients had died of preexisting cancer or cardiovascular disease. Recurrent venous thromboembolism was uncommon. Symptoms in the leg affected by the index thrombosis were common, however, and were associated with worse health-related quality of life. (Arch Intern Med. 1995;155:1031-1037)
Rebecca J. Beyth (Mon,) conducted a cohort in acute deep-vein thrombosis (n=124). Acute deep-vein thrombosis was evaluated on Death. Six to 8 years after acute deep-vein thrombosis, 42% of patients had died, primarily from preexisting cancer or cardiovascular disease, while recurrent venous thromboembolism occurred in 15%.
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