Patients with severe mental illness are at increased risk of early-onset coronary artery disease but are less likely to receive evidence-based management and invasive revascularization compared to the general population.
Patients with severe mental illness are at high risk for early-onset coronary artery disease but face significant systemic and biological barriers to receiving standard invasive management and secondary prevention, highlighting a critical treatment gap.
Severe mental illnesses (SMI), such as schizophrenia and bipolar disorder, are associated with a decrease in life expectancy of up to two decades compared with the general population, with cardiovascular disease as the leading cause of death. SMI is associated with increased cardiovascular risk profile and early onset of incident cardiovascular disease. Following an acute coronary syndrome, patients with SMI have a worse prognosis, but are less likely to receive invasive treatment. In this narrative review, the management of coronary artery disease in patients with SMI is discussed, and avenues for future research are highlighted.
To et al. (Mon,) conducted a review in Coronary Artery Disease in Severe Mental Illness. Severe mental illness vs. General population was evaluated. Patients with severe mental illness are at increased risk of early-onset coronary artery disease but are less likely to receive evidence-based management and invasive revascularization compared to the general population.