ABSTRACT Introduction Hospitalization is a critical phase in the management of inflammatory bowel disease (IBD). Hospitalized patients with IBD have varied outcomes despite advances in therapy. This study examined the treatment patterns and short‐term clinical outcomes of hospitalized patients with IBD. Methods A prospective cross‐sectional study was conducted, analyzing data from all patients with IBD admitted to the Department of Gastroenterology at Bir Hospital, National Academy of Medical Sciences, Kathmandu, Nepal, from May 2024 to September 2025. Statistical data were analyzed using IBM SPSS Statistics 23 (SPSS Inc., Chicago, Illinois, USA). Continuous measurements were presented as mean ± standard deviation (SD) for normally distributed data and median (range; interquartile range, IQR) for data that were not normally distributed, whereas categorical measurements were presented as frequencies and percentages. Results Overall, patients with IBD constituted 1.6% ( n = 37) of all admissions to the gastroenterology ward for any indication. Among these, 25 (68%) patients had ulcerative colitis (UC) and 12 (32%) had Crohn's disease (CD). Thirty five (95%) of in‐hospital patients with IBD showed a clinical response to treatment. Among these patients, 24 (65%) responded to conventional therapies, with a higher response rate among those with UC, whereas 9 (27%) required advanced therapies such as biologics and Janus kinase inhibitors. Surgical intervention, specifically urgent colectomy, led to a clinical response in two patients. In‐hospital mortality occurred in two (5%) of the patients, with one death each in the UC and CD groups. Conclusions Most (2/3rd) hospitalized patients with IBD responded to conventional therapy; one third required advanced therapy or surgery. In‐hospital mortality was high at 5%, probably related to delayed diagnosis, limited access to advanced treatments, and disease‐related complications.
Yadav et al. (Wed,) studied this question.