Striated Muscle Fibers: Facilitation of Contraction at Short Lengths by Caffeine

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Abstract

One of the factors evidently responsible for decreasing the force of muscle contraction with shortening is inactivation of the myofibrils in the core of a muscle fiber. Caffeine antagonizes this inactivation and, correspondingly, changes the length-force relationship at short muscle lengths.

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Cite This Study

Rüdel et al. (Fri,) studied this question.

synapsesocial.com/papers/6a23d9c32dc9ee5f679f03f3 https://doi.org/https://doi.org/10.1126/science.172.3981.387

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Striated Muscle Fibers: Inactivation of Contraction Induced by Shortening1970 · 132 citations
2The variation in isometric tension with sarcomere length in vertebrate muscle fibres1966 · 3,140 citations
3The influence of stimulus parameters on contractions of isolated frog muscle fibres1969 · 27 citations
4Potassium contractures in single muscle fibres1960 · 534 citations
5Contraction enhancement in skeletal muscles of normal and dystrophic mice1965 · 18 citations

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