What does this research mean for the field?

An e-health-enhanced integrated model of care significantly improves glycemic management compared to usual care among Latino adults with type 2 diabetes. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This research aims to assess the impact of an e-health-enhanced integrated model of care on glycemic control among Latino adults with type 2 diabetes.

June 7, 2026

1056-OR: Integrating Behavioral, Medical, and E-health Care to Improve Glycemic Management among Latino Adults: Results from the LUNA-E Randomized Clinical Trial

Key Points

This research aims to assess the impact of an e-health-enhanced integrated model of care on glycemic control among Latino adults with type 2 diabetes.
Two-arm randomized controlled trial including 92 participants in e-health intervention and 88 in clinic-based care coordination.
A propensity score-matched usual care group (n=90) served as external comparison.
HbA1c levels were measured at baseline, 3, 6, and 12 months with multi-level models analyzing rate of change.
IMC group showed a significant HbA1c decline compared to the UC group (B = -.07, 95% CI -.13,-.03).
Both IMC and CC groups showed improvements in HbA1c per month (∆HbA1c IMC = -.10, 95% CI -.15,-.06; ∆HbA1c CC = -.07, 95% CI -.11,-.02), while the UC group did not exhibit significant improvement (∆HbA1c UC = -.02, 95% CI -.06,.02).
The IMC intervention resulted in larger HbA1c improvements compared to clinic-based care.

Abstract

Introduction and Objective: Integrated models of care (IMC) for type 2 diabetes (T2D) can be cost-efficient and effective in improving glycemic management (HbA1c), yet Latinos can face barriers to receiving these in-person services. We examined the effect of an e-health-enhanced IMC intervention on HbA1c among Latino adults with T2D from a federally qualified health center in San Diego, CA. Methods: A two-arm randomized controlled trial (2023-25) compared an e-health IMC intervention (n=92) to clinic-based care coordination (CC, n=88); a third, propensity score-matched usual care group (UC, n=90) served as an external comparison. The IMC intervention included care coordination, virtual integrated medical and behavioral health visits, and asynchronous diabetes education and support. The CC arm received clinic-based care coordination services only. Participants were followed for 12-months; HbA1c was collected at baseline, 3, 6, and 12 months, and/or abstracted from medical records. Multi-level models estimated differences in HbA1c rate of change (time-by-group interaction effects). Within group slopes were calculated to estimate change in HbA1c per month. Results: Participants were mostly female (69%), Spanish-speaking (88%), and averaged 58 years of age (SD=10.42). A significant group-by-time interaction showed a steeper HbA1c decline in the IMC versus UC group (B = -.07, 95% CI -.13,-.03). Slopes did not differ significantly between the IMC and CC arms (B = -.04, 95% CI -.11,.02) and CC and UC arms (B = -.03, 95% CI -.09,.03), respectively. Within-group slopes showed significant HbA1c improvements in the IMC (∆HbA1c/month=-.10, 95% CI -.15,-.06) and CC arms (∆HbA1c/month=-.07, 95% CI -.11,-.02) but not in UC (∆HbA1c/month=-.02, 95% CI -.06,.02). Conclusion: Although both IMC and CC improved HbA1c, the IMC group experienced larger improvements. Further research should identify the specific components driving these effects to optimize implementation in diverse settings. Disclosure H. Mendez-Rodriguez: None. C.E. Rosas: None. P. Mendoza: None. G. Toba: None. L.C. Gallo: None. F. Munoz: None. S. Roesch: None. G.A. Talavera: None. L. Camacho: None. P. Rocha: None. J. Roesch: None.

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1056-OR: Integrating Behavioral, Medical, and E-health Care to Improve Glycemic Management among Latino Adults: Results from the LUNA-E Randomized Clinical Trial

Key Points

Abstract

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