Introduction and Objective: Limited data exists on how maternal and paternal diabetes and obesity jointly influence early childhood obesity. We analyzed data from 97,317 singletons born 2008-2022 to assess associations between parental pre-existing diabetes (PreDM), maternal gestational diabetes (GDM) diagnosed early (≤26wks) and late (26wks), pre-pregnancy obesity, weight changes during pregnancy and postpartum, and breastfeeding with child overweight status at age 2. Methods: Robust Poisson regression was used to assess associations adjusted for covariates. Results: PreDM prevalence was 4.0% (mothers) and 3.8% (fathers); GDM was 11.3% (4.2% early and 7.1% late). Pre-pregnancy obesity affected 28.0% mothers and 38.4% fathers. During pregnancy, 33.7% mothers met IOM weight gain guidelines; fathers gained 2.6±11.3 (mean±SD) lb. By 2 yrs postpartum, mothers lost 19.4±17.1 lb; fathers gained 1.4±15.1 lb. Breastfeeding ≥6 months occurred in 62.6% mothers. At age 2, 16.2% children were overweight (BMI %tile =85%). Figure 1 depicts relative risk (RR) of child overweight at age 2 associated with each parental measure adjusted for covariates (panel A) and the further adjusted RR after including all parental measures in one model. Conclusion: Results indicated parental obesity was the strongest predictor of child overweight at age 2, while guideline-concordant maternal weight gain and ≥6 months of breastfeeding were protective. Parental PreDM independently increased the risk. Disclosure A. Xiang: None. J.C. Lin: None. T. Chow: None. M. Martinez: None.
XIANG et al. (Fri,) studied this question.
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