ABSTRACTHerbal based cosmetic formulations have gained for safety, biocompatibility, and efficacy in managing scalp disorder. Dandrufflinked to Malassezia overgrowth, requires long-term treatment. This study developed, optimized, and evaluated a polyherbal anti-dandruff shampoo using extracts of Piper nigrum, Moringa oleifera and Momordica charantia for their antifungal, anti-inflammatory, antioxidant and antimicrobial properties. Extracts were prepared via decoction and maceration. Seventeen formulations (F1-F17) were developed with varying extract concentrations and optimized using Box-Behnken Design. Fivepromising ones underwent comprehensive evaluation for physicochemical properties: colour, clarity, odour, pH, viscosity,surface tension, solid content, wetting time, foam capacity, foam stability, and antifungal activity. Formulation F16 excelledwith pH ̴ 6.9, optimal viscosity, low surface tension, excellent foaming/stability, effective wetting and antifungal activity. Itoffers dandruff control, hair conditioning, and scalp health without irritation, positioning polyherbal shampoos as safealternatives to synthetics.
Sneha Varughese, Saniya Thomas, Malavika Minil, Arundhathy A, Anjana Anil Kumar, Dr. Shajan Abraham (Wed,) studied this question.
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