LC–MS/MS profiling dataset of Indonesian Citrus peel extracts: extraction yield, antioxidant activity, and annotated compounds

Citrus peel extracts (CPEs) are widely studied as sources of antioxidant-related phytochemicals, yet their composition may vary across Citrus varieties and extraction solvents. Here we report a dataset describing extraction yield, DPPH antioxidant activity (IC₅₀), and LC–MS/MS chemical profiles of peel extracts from five Indonesian-grown Citrus varieties (Chokun, Fremont, Lemon, Santang, and Sunkist) prepared using ethyl acetate and ethanol. Yield and DPPH IC₅₀ values are provided as mean ± SD from two biological replicates (n = 2), while LC–MS/MS profiling and peak area–based relative abundance are reported as a single measurement per condition (n = 1). Across the profiled samples, prominent annotated compounds included nobiletin, tangeretin, retusin, and scopoletin. Ethanol extracts of Chokun and Fremont showed lower IC₅₀ values (0.286 and 0.357 mg/mL, respectively) under the assay conditions used. Exploratory PCA is included to summarize variation in relative abundance profiles between solvents and varieties. This Data Note provides well-documented measurements and profiles that can be reused for comparative and hypothesis-generating studies on Citrus peel phytochemistry and antioxidant assays.