Microbiological Profile and Clinical Correlates in Fournier’s Gangrene: A Retrospective Single-Center Study

Key Points

• This study aims to analyze the microbiological spectrum of Fournier's gangrene and its association with diabetes, age, and clinical outcomes.
• Conducted a retrospective analysis of 50 Fournier's gangrene patients from 2012 to 2023.
• Used multinomial logistic regression to examine the relationship between microbiological spectra and clinical factors.
• Applied ARIMA model for evaluating temporal shifts in pathogen prevalence.
• Diabetes was present in 40% of patients and significantly associated with anaerobic pathogens (RRR: 8.0; 95% CI: 1.17–54.7).
• 64% of patients required ICU treatment post-surgery, with a median ICU stay of 4.5 days.
• Mortality rate was 14% among the cohort, with median hospitalization lasting 12 days.