Fournier's gangrene is a life-threatening necrotizing fasciitis affecting the soft tissues of the perineal, genital, and perianal regions. It progresses rapidly due to microvascular thrombosis and extensive tissue necrosis. The condition occurs more frequently in men and is associated with comorbidities such as diabetes mellitus, alcoholism, immunosuppression, obesity, and chronic kidney disease. Its polymicrobial etiology, involving both aerobic and anaerobic bacteria, promotes tissue destruction and sepsis. Management requires a multidisciplinary approach including hemodynamic resuscitation, broad-spectrum antibiotic therapy, and aggressive repeated surgical debridement.
Almaraz et al. (Fri,) studied this question.